A lamb that is born showing a severe congenital malformation such that it developed 2 spines within the cervical and thoracic vertebrae regions. These duplicated spinal cords were attached to one head at its anterior side and joined more posterior into one spine in the lumbar and sacral regions. How is this possible?
Articulate what the cellular and molecular mechanisms are enabling the creation of 2 spinal cords only within the position of the cervical and thoracic regions of this lamb. you have 2 options to answer this question. (Pick A or B)
A: Describe 2 separate models in which the first hypothesis would focus on how early developmental events (that may include mechanisms of maternal contributions, gastrulation, and/or axis determination) and a second hypothesis focused on issues of neural tube formation.
B: Alternatively, you can describe one model that incorporates both early developmental patterning mechanisms and those of neural tube formation.
Book used for this course is Developmental Biology by Berresi and Gilbert. 12th edition.